Alzheimer’s Disease and Periodontitis
Recently, chronic periodontitis has been associated with several systemic diseases including Alzheimer’s disease (AD). Studies suggest that peripheral infection/inflammation might affect the inflammatory state of the central nervous system. Inflammation within the brain is thought to play a pivotal role.
Chronic periodontitis is a prevalent peripheral infection that is associated with gram-negative anaerobic bacteria and the elevation of serum inflammatory markers including C-reactive protein. Research has identified several potential mechanisms through which chronic periodontitis can contribute to the clinical onset and progression of dementia and Alzheimer’s disease. Further studies have shown that people with cognitive impairment have poor dental health. Because chronic periodontitis is a treatable infection, early detection, and consistent oral hygiene is suggested.
According to Dr. Pamela McClain, President of the American Academy of Periodontology and a practicing periodontist in Aurora, Colorado, “If left untreated, periodontal disease can lead to tooth loss and may also interfere with other systems of the body. Several research studies have indicated that one’s periodontal health may be related to overall health. Therefore, it is crucial that you do everything you can to establish good periodontal health.”
Studies about Periodontitis have shown…
A Recent study has found a link between gum disease and early stages of Alzheimer’s Disease.
Periodontitis or gum disease is common in older people and may become more common in Alzheimer’s disease because of a reduced ability to take care of oral hygiene as the disease progresses. Higher levels of antibodies to periodontal bacteria are associated with an increase in levels of inflammatory molecules elsewhere in the body, which in turn has been linked to greater rates of cognitive decline in Alzheimer’s disease in previous studies.
Dr. Mark Ide from the Dental Institute at King’s College London who authored the study wrote:
“Previous studies have also shown that patients with Alzheimer’s Disease have poorer dental health than others of similar age and that the more severe the dementia the worse the dental health, most likely reflecting greater difficulties with taking care of oneself as dementia becomes more severe..”
Read more at sciencedaily.com